Department of Dermatology, Eastern Virginia Medical School, Norfolk, Virginia 23507, USA.
J Am Acad Dermatol. 2010 Feb;62(2):315-8. doi: 10.1016/j.jaad.2009.05.046. Epub 2009 Aug 8.
Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare serious adverse effect associated with a variety of medications. We present a case of minocycline-induced DRESS syndrome, which resulted in acute renal failure, transient thyroiditis, and transaminitis, and a persistent lymphocytic myocarditis resulting in congestive heart failure. To our knowledge, this is the third reported case of minocycline-induced myocarditis. Additionally, we report successful plasmapheresis and rituximab treatment for minocycline-induced myocarditis associated with the DRESS syndrome.
药物反应伴嗜酸性粒细胞增多和全身性症状（DRESS）综合征是一种与多种药物相关的罕见严重不良反应。我们报告了一例米诺环素诱导的 DRESS 综合征，其导致急性肾衰竭、短暂性甲状腺炎和转氨基酶升高，以及持续性淋巴细胞性心肌炎导致充血性心力衰竭。据我们所知，这是第三例报告的米诺环素诱导性心肌炎病例。此外，我们报告了成功的血浆置换和利妥昔单抗治疗与 DRESS 综合征相关的米诺环素诱导性心肌炎。
