Georgopoulos Gerasimos Th, Papaconstantinou Dimitrios, Niskopoulou Maria, Moschos Marilita, Georgalas Ilias, Koutsandrea Chrysanthi
Glaucoma Department, Medical School, Athens University, Athens, Greece.
Clin Ophthalmol. 2008 Dec;2(4):817-20. doi: 10.2147/opth.s4031.
Despite a significant body of research, no consistency on postoperative foveal thickness as measured by optical coherence tomography (OCT), can be recorded. The purpose of our study was to evaluate the effect of uncomplicated cataract surgery in the thickness of the retina in the foveal area during the early postoperative period.
In a prospective study, 79 eyes were assessed by OCT, on day 1, and weeks 2 and 4 after uncomplicated phacoemulsification with intraocular lens implantation in the Athens University Clinic. The outcome measure was the thickness of the retina in the foveal area.
The thickness of the retina preoperatively is significantly smaller (150.4 +/- 18.8) (p < 0.05) than the thickness of the retina on day 1 (171.8 +/- 21) and week 2 (159.7 +/- 19) and returned to the initial levels on week 4 (152 +/- 17.1). The estimated correlation coefficients between preoperative and postoperative thickness of the retina were significant (p < 0.05). Conversely, no association was found between postoperative visual acuity and thickness of the retina, neither between the phacoemulsification energy and retinal thickness. Operation time, although inversely related with postoperative visual acuity, was not associated with the thickness of the retina.
Following phacoemulsification, an increase in the foveal thickness was detected in the early postoperative period, quantified and followed up by OCT. The foveal thickness returned to the preoperative level, 1 month following surgery in our study. No association was shown between intraoperative parameters and increased postoperative retinal thickness.
尽管已有大量研究,但通过光学相干断层扫描(OCT)测量的术后黄斑厚度并无一致性记录。我们研究的目的是评估单纯性白内障手术对术后早期黄斑区视网膜厚度的影响。
在一项前瞻性研究中,对雅典大学诊所79只接受单纯性超声乳化白内障吸除联合人工晶状体植入术的眼睛,在术后第1天、第2周和第4周进行OCT评估。观察指标为黄斑区视网膜厚度。
术前视网膜厚度(150.4±18.8)显著小于术后第1天(171.8±21)和第2周(159.7±19),并在第4周恢复至初始水平(152±17.1)。术前与术后视网膜厚度的估计相关系数具有显著性(p<0.05)。相反,术后视力与视网膜厚度之间、超声乳化能量与视网膜厚度之间均未发现关联。手术时间虽与术后视力呈负相关,但与视网膜厚度无关。
超声乳化白内障吸除术后早期,黄斑厚度增加,可通过OCT进行量化和随访。在我们的研究中,术后1个月黄斑厚度恢复至术前水平。术中参数与术后视网膜厚度增加之间未显示出关联。