Sandoval Helga P, Fernández de Castro Luis E, Vroman David T, Solomon Kerry D
Magill Research Center for Vision Correction, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.
Clin Ophthalmol. 2007 Dec;1(4):367-71.
The non-steroidal anti-inflammatory drug (NSAID) ketorolac tromethamine 0.4% ophthalmic solution, a recent reformulation containing 20% less active ingredient that the original formulation, is indicated for the reduction of ocular pain and burning/stinging following corneal refractive surgery. Clinical studies have shown ketorolac tromethamine 0.4% to be as effective as ketorolac tromethamine 0.5% to control inflammation after cataract surgery including prevention of cystoid macular edema (CME). Its efficacy to inhibit miosis during cataract surgery as well as its role in the treatment of dry eye has been reported. The purpose of this paper is to review the use of ketorolac tromethamine 0.4% in the treatment of post-surgical inflammation following cataract and refractive surgery.
非甾体抗炎药（NSAID）酮咯酸氨丁三醇0.4%滴眼液是一种近期重新配方的药物，其活性成分比原配方少20%，适用于减轻角膜屈光手术后的眼痛和烧灼/刺痛感。临床研究表明，0.4%酮咯酸氨丁三醇在控制白内障手术后的炎症（包括预防黄斑囊样水肿[CME]）方面与0.5%酮咯酸氨丁三醇同样有效。据报道，它在白内障手术期间抑制瞳孔缩小的功效以及在治疗干眼症中的作用。本文的目的是综述0.4%酮咯酸氨丁三醇在白内障和屈光手术后炎症治疗中的应用。
