Department of Radiation Oncology, Massachusetts General Hospital, Francis F. Burr Proton Therapy Center, Boston, MA, USA.
Cancer J. 2009 Jul-Aug;15(4):292-7. doi: 10.1097/PPO.0b013e3181b11dd0.
The technology that is used for the production and delivery of therapeutic proton beams is reviewed. Increased interest in this treatment modality has inspired a new generation of technology development and research into methods that will make proton treatment facilities more widely available (less expensive) and more efficient. Proton beam therapy has been in use for more than 40 years; it remains a treatment modality of interest because it provides a highly conformal dose distribution to a wide variety of disease sites and the potential for improving clinical outcomes. Recent advances in beam scanning technology may represent the ultimate in external beam radiotherapy dose conformality and treatment delivery efficiency. We describe how this new technology can be integrated into a proton therapy facility.
本文回顾了用于治疗质子束产生和输送的技术。对这种治疗方式的浓厚兴趣激发了新一代技术的发展和研究，旨在使质子治疗设施更广泛地应用（成本更低廉）且更高效。质子束治疗已经使用了 40 多年；它仍然是一种有吸引力的治疗方式，因为它为广泛的疾病部位提供了高度适形的剂量分布，并有改善临床结果的潜力。最近在束流扫描技术方面的进展可能代表了外照射放疗剂量适形性和治疗输送效率的极致。我们描述了如何将这项新技术集成到质子治疗设施中。
