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在SV40转化的人成纤维细胞与小鼠LMTK细胞之间形成的杂种中,“T”抗原与任何特定人类染色体之间缺乏相关性。

A lack of correlation between 'T' antigen and any particular human chromosome in hybrids made between SV40 transformed human fibroblasts and mouse LMTK cells.

作者信息

Webb T, Harding M

出版信息

Cancer Lett. 1977 Jul;3(1-2):15-21. doi: 10.1016/s0304-3835(77)93784-3.

Abstract

Lines of hybrid cells were established by fusion of mouse LMTK- cells with SV40 transformed human fibroblasts. The lines were examined for the presence of SV40 'T' antigen and the human chromosomes they carried identified by Giemsa banding. No significant correlation could be found between any particular human chromosome and the presence of SV40 virus.

摘要

通过将小鼠LMTK-细胞与SV40转化的人成纤维细胞融合建立了杂交细胞系。检测这些细胞系中SV40“T”抗原的存在情况,并通过吉姆萨显带鉴定它们所携带的人类染色体。未发现任何特定人类染色体与SV40病毒的存在之间存在显著相关性。

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