一锅法从芳基氨基酮和乙烯基膦盐合成 4-芳基喹啉。
One-pot synthesis of 4-arylquinolines from aromatic aminoketones and vinylphosphonium salts.
机构信息
Department of Chemistry, Mazandaran University, PO Box 453, Babolsar, Iran.
出版信息
Mol Divers. 2010 Aug;14(3):569-74. doi: 10.1007/s11030-009-9188-y. Epub 2009 Aug 13.
PMID:19680770
Abstract
The addition of acetylenic esters to aromatic amines such as 2-amino benzophenone derivatives in the presence of triphenylphosphine leads to highly functionalized phosphoranes, which undergo an intramolecular Wittig reaction following oxidation to produce quinoline derivatives.
摘要
在三苯基膦的存在下，将炔基酯添加到芳族胺（如 2-氨基二苯甲酮衍生物）中，得到高度官能化的磷叶立德，这些磷叶立德在氧化后进行分子内 Wittig 反应，生成喹啉衍生物。
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