乙烯基鏻盐和2-氨基乙烯基鏻盐——制备及其在有机合成中的应用

Vinylphosphonium and 2-aminovinylphosphonium salts - preparation and applications in organic synthesis.

作者信息

Kuźnik Anna, Mazurkiewicz Roman, Fryczkowska Beata

机构信息

Department of Organic and Bioorganic Chemistry and Biotechnology, Silesian University of Technology, B. Krzywoustego 4, 44-100 Gliwice, Poland.

Biotechnology Center of Silesian University of Technology, B. Krzywoustego 8, 44-100 Gliwice, Poland.

出版信息

Beilstein J Org Chem. 2017 Dec 15;13:2710-2738. doi: 10.3762/bjoc.13.269. eCollection 2017.

DOI:10.3762/bjoc.13.269

PMID:29564008

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5753072/

Abstract

The main synthetic routes towards vinylphosphonium salts and their wide applications in organic synthesis are discussed in this review. Particular attention is paid to the use of these compounds as building blocks for the synthesis of carbo- and heterocyclic systems after their prior transformation into the corresponding phosphorus ylides, followed by the intramolecular Wittig reaction with various types of nucleophiles containing a carbonyl function in their structures.

摘要

本文综述了乙烯基鏻盐的主要合成路线及其在有机合成中的广泛应用。特别关注了这些化合物在预先转化为相应的磷叶立德后，作为合成碳环和杂环体系的结构单元的用途，随后与结构中含有羰基官能团的各种类型亲核试剂进行分子内维蒂希反应。