评估葡萄牙奶牛场从饮用水、尿液、毛发和饲料样本中非法使用克仑特罗的情况。

Evaluation of the illegal use of clenbuterol in Portuguese cattle farms from drinking water, urine, hair and feed samples.

机构信息

Grupo de Bromatologia, Centro de Estudos Farmaceuticos, Faculdade de Farmacia da Universidade de Coimbra, 3000-295 Coimbra, Portugal.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Jun;26(6):814-20. doi: 10.1080/02652030902729908.

DOI:10.1080/02652030902729908

PMID:19680955

Abstract

The recent discovery of clenbuterol contamination in Portuguese food led to the specific inspection of 16 cattle farms for beta-agonists, involving the analysis of a total of 486 samples (78 feed, 106 drinking water, 168 urine and 134 hair). The samples were screened for the beta-agonists: bromobuterol, cimaterol, clenbuterol, clenpenterol, clenproperol, hydroxymethylclenbuterol, mapenterol, salbutamol and terbutaline. Only clenbuterol was found in all analyzed matrices and the most likely method of illegal administration to animals was through drinking water. Of all samples analysed, 14.15% of drinking water were found positive in the range 0.03-3.80 mg l(-1) clenbuterol. Inclusion of hair samples in the Portuguese plan for clenbuterol residue control in live animals is discussed.

摘要

最近在葡萄牙食品中发现克伦特罗污染，这导致对 16 个奶牛场的β-激动剂进行了专门检查，共分析了 486 个样本（78 个饲料、106 个饮用水、168 个尿液和 134 个毛发）。这些样本被筛选出β-激动剂：溴布特罗、西马特罗、克伦特罗、克伦特罗醇、克仑丙特罗、羟甲基克伦特罗、马布特罗、沙丁胺醇和特布他林。所有分析的基质中均发现克伦特罗，最有可能的非法给动物用药方式是通过饮用水。在所分析的所有样本中，饮用水中有 14.15%的浓度在 0.03-3.80mg/L 之间呈阳性。讨论了在葡萄牙活畜克伦特罗残留控制计划中纳入毛发样本的问题。