• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

评估葡萄牙奶牛场从饮用水、尿液、毛发和饲料样本中非法使用克仑特罗的情况。

Evaluation of the illegal use of clenbuterol in Portuguese cattle farms from drinking water, urine, hair and feed samples.

机构信息

Grupo de Bromatologia, Centro de Estudos Farmaceuticos, Faculdade de Farmacia da Universidade de Coimbra, 3000-295 Coimbra, Portugal.

出版信息

Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Jun;26(6):814-20. doi: 10.1080/02652030902729908.

DOI:10.1080/02652030902729908
PMID:19680955
Abstract

The recent discovery of clenbuterol contamination in Portuguese food led to the specific inspection of 16 cattle farms for beta-agonists, involving the analysis of a total of 486 samples (78 feed, 106 drinking water, 168 urine and 134 hair). The samples were screened for the beta-agonists: bromobuterol, cimaterol, clenbuterol, clenpenterol, clenproperol, hydroxymethylclenbuterol, mapenterol, salbutamol and terbutaline. Only clenbuterol was found in all analyzed matrices and the most likely method of illegal administration to animals was through drinking water. Of all samples analysed, 14.15% of drinking water were found positive in the range 0.03-3.80 mg l(-1) clenbuterol. Inclusion of hair samples in the Portuguese plan for clenbuterol residue control in live animals is discussed.

摘要

最近在葡萄牙食品中发现克伦特罗污染,这导致对 16 个奶牛场的β-激动剂进行了专门检查,共分析了 486 个样本(78 个饲料、106 个饮用水、168 个尿液和 134 个毛发)。这些样本被筛选出β-激动剂:溴布特罗、西马特罗、克伦特罗、克伦特罗醇、克仑丙特罗、羟甲基克伦特罗、马布特罗、沙丁胺醇和特布他林。所有分析的基质中均发现克伦特罗,最有可能的非法给动物用药方式是通过饮用水。在所分析的所有样本中,饮用水中有 14.15%的浓度在 0.03-3.80mg/L 之间呈阳性。讨论了在葡萄牙活畜克伦特罗残留控制计划中纳入毛发样本的问题。

相似文献

1
Evaluation of the illegal use of clenbuterol in Portuguese cattle farms from drinking water, urine, hair and feed samples.评估葡萄牙奶牛场从饮用水、尿液、毛发和饲料样本中非法使用克仑特罗的情况。
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2009 Jun;26(6):814-20. doi: 10.1080/02652030902729908.
2
Development and validation of a liquid chromatography tandem mass spectrometry method for the analysis of beta-agonists in animal feed and drinking water.建立并验证了一种用于动物饲料和饮用水中β-激动剂分析的液相色谱-串联质谱法。
J Chromatogr A. 2010 Sep 24;1217(39):6061-8. doi: 10.1016/j.chroma.2010.07.034. Epub 2010 Aug 5.
3
Detection of illegal clenbuterol use in calves using hair analysis. Application in meat quality control.
J Chromatogr B Biomed Sci Appl. 1997 Dec 5;703(1-2):85-95. doi: 10.1016/s0378-4347(97)00406-4.
4
Hyphenation of coupled-column liquid chromatography and thermospray tandem mass spectrometry for the rapid determination of beta 2-agonist residues in bovine urine using direct large-volume sample injection. Set-up of single-residue methods for clenbuterol and salbutamol.联用柱液相色谱与热喷雾串联质谱联用技术,通过直接大体积进样快速测定牛尿中β-2激动剂残留。建立克伦特罗和沙丁胺醇的单残留检测方法。
J Mass Spectrom. 1996 Apr;31(4):418-26. doi: 10.1002/(SICI)1096-9888(199604)31:4<418::AID-JMS315>3.0.CO;2-F.
5
Application of an enzyme-linked immunosorbent assay for the detection of clenbuterol residues in swine urine and feeds.一种用于检测猪尿液和饲料中盐酸克伦特罗残留的酶联免疫吸附测定法的应用。
J Environ Sci Health B. 2007 Feb;42(2):173-7. doi: 10.1080/03601230601123508.
6
Development of a lateral-flow assay for rapid screening of the performance-enhancing sympathomimetic drug clenbuterol used in animal production; food safety assessments.开发一种用于快速筛查动物生产中使用的增强性能的拟交感神经药物克伦特罗的侧向流动检测方法;食品安全评估。
Asia Pac J Clin Nutr. 2007;16 Suppl 1:106-10.
7
A fast immunoassay for the screening of beta-agonists in hair.一种用于毛发中β-激动剂筛查的快速免疫测定法。
Analyst. 1998 Dec;123(12):2707-10. doi: 10.1039/a805041d.
8
Possible contamination with clenbuterol from treated veal calves to untreated pen mates.来自经过处理的犊牛的克伦特罗可能污染未经处理的同栏猪。
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2013;30(6):1063-7. doi: 10.1080/19440049.2013.781276. Epub 2013 May 8.
9
Beta-agonists in animal feed. I: First intercomparison of methods of analysis for clenbuterol in animal feed materials.动物饲料中的β-激动剂。I:动物饲料原料中克伦特罗分析方法的首次比对
Food Addit Contam. 1996 Jul;13(5):477-92. doi: 10.1080/02652039609374435.
10
Effects of frozen storage on the recovery of clenbuterol from urine samples for official control.冷冻储存对用于官方控制的尿样中克伦特罗回收率的影响。
Food Addit Contam. 2002 Nov;19(11):1010-4. doi: 10.1080/02652030210157673.

引用本文的文献

1
Current Advances in Immunoassays for the Detection of β-Agonists.检测β-激动剂的免疫分析方法的当前进展
Foods. 2022 Mar 11;11(6):803. doi: 10.3390/foods11060803.
2
Comparison of beta-ligands used in cattle production: structures, safety, and biological effects.用于牛生产的β-激动剂的比较:结构、安全性和生物学效应。
J Anim Sci. 2021 Aug 1;99(8). doi: 10.1093/jas/skab094.
3
Metabolic Effects of Clenbuterol and Salbutamol on Pork Meat Studied Using Internal Extractive Electrospray Ionization Mass Spectrometry.采用内提取电喷雾电离质谱法研究克仑特罗和沙丁胺醇对猪肉代谢的影响。
Sci Rep. 2017 Jul 11;7(1):5136. doi: 10.1038/s41598-017-05496-6.