St Mary's Hospital, Imperial Healthcare NHS trust, London, UK.
BJOG. 2009 Nov;116(12):1678-82. doi: 10.1111/j.1471-0528.2009.02285.x. Epub 2009 Aug 14.
Maternal vitamin D deficiency is a significant public health issue. This retrospective multicentre audit was undertaken to identify the scale of maternal vitamin D deficiency in London, using infant vitamin D deficiency as a surrogate marker. During January 2006 to June 2008, 74 infants presented with symptomatic vitamin D deficiency, a prevalence of 1.6 per 1000 deliveries in London. Of these, 49% were hypocalcaemic at presentation and 27% had hypocalcaemic seizures. A telephone survey in June 2008 showed that no London National Health Service antenatal units had departmental guidelines on vitamin D. This audit is presented to raise awareness of current recommendations and the sequelae of maternal vitamin D deficiency.
母体维生素 D 缺乏是一个重大的公共卫生问题。本回顾性多中心审计旨在通过婴儿维生素 D 缺乏作为替代标志物，确定伦敦母体维生素 D 缺乏的严重程度。在 2006 年 1 月至 2008 年 6 月期间，74 名婴儿出现症状性维生素 D 缺乏症，伦敦的发病率为每 1000 例分娩 1.6 例。其中，49%在就诊时出现低钙血症，27%出现低钙血症性癫痫发作。2008 年 6 月的电话调查显示，伦敦国民保健署的产前单位没有关于维生素 D 的部门指南。本审计旨在提高对当前建议和母体维生素 D 缺乏的后果的认识。
