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采用骨块移植进行下颌后缩垂直骨增量:取自髂嵴的骨 vs. 牛无机骨。一项随机对照临床试验的加载后 1 年的临床和组织学结果。

Vertical ridge augmentation of the atrophic posterior mandible with interpositional bloc grafts: bone from the iliac crest vs. bovine anorganic bone. Clinical and histological results up to one year after loading from a randomized-controlled clinical trial.

机构信息

Department of Periodontology and Implantology, University of Bologna, Bologna, Italy.

出版信息

Clin Oral Implants Res. 2009 Dec;20(12):1386-93. doi: 10.1111/j.1600-0501.2009.01765.x. Epub 2009 Aug 4.

Abstract

OBJECTIVES

To compare two different techniques for vertical bone augmentation of the posterior mandible: bone blocs from the iliac crest vs. anorganic bovine bone blocs used as inlays.

MATERIALS AND METHODS

Ten partially edentulous patients having 5-7 mm of residual crestal height above the mandibular canal had their posterior mandibles randomly allocated to both interventions. After 4 months implants were inserted, and after 4 months, provisional prostheses were placed. Definitive prostheses were delivered after 4 months. Histomorphometry of samples trephined at implant placement, prosthesis and implant failures, any complication after loading and peri-implant marginal bone-level changes were assessed by masked assessors. All patients were followed up to 1 year after loading.

RESULTS

Four months after bone augmentation, there was statistically significant more residual graft (between 10% and 13%) in the Bio-Oss group. There were no statistically significant differences in failures and complications. Two implants could not be placed in one patient augmented with autogenous bone because the graft failed whereas one implant and its prosthesis of the Bio-Oss group failed after loading. After implant loading only one complication (peri-implantitis) occurred at one implant of the autogenous bone group. In 16 months (from implant placement to 1 year after loading), both groups lost statistically significant amounts of peri-implant marginal bone: 0.82 mm in the autogenous bone group and 0.59 mm in the Bio-Oss group; however, there were no statistically significant differences between the groups.

CONCLUSIONS

Both procedures achieved good results, but the use of bovine blocs was less invasive and may be preferable than harvesting bone from the iliac crest.

摘要

目的

比较两种不同的后下颌骨垂直骨增量技术:髂嵴骨块与用作嵌体的无机牛骨块。

材料和方法

10 名部分无牙患者,下颌管上方有 5-7mm 的剩余牙槽嵴高度,将其下颌后部分别随机分配到两种干预措施中。4 个月后植入物被插入,4 个月后,临时修复体被放置。4 个月后交付最终修复体。通过盲法评估员评估在植入物放置、修复体和植入物失败、加载后的任何并发症以及种植体周围边缘骨水平变化时取出的样本的组织形态计量学。所有患者在加载后随访 1 年。

结果

在骨增量后 4 个月,Bio-Oss 组的剩余移植物(10%至 13%之间)统计学上显著更多。在失败和并发症方面没有统计学上的显著差异。一名患者因移植物失败而无法在自体骨增强的情况下放置两个植入物,而 Bio-Oss 组的一个植入物及其修复体在加载后失败。在植入物加载后,仅在自体骨组的一个植入物上发生了一种并发症(种植体周围炎)。在 16 个月(从植入物放置到加载后 1 年),两组均统计学显著损失种植体周围边缘骨:自体骨组为 0.82mm,Bio-Oss 组为 0.59mm;然而,两组之间没有统计学显著差异。

结论

两种手术都取得了良好的效果,但使用牛骨块侵入性较小,可能比从髂嵴采集骨块更可取。

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