Evsikov Alexei V, Dolan Mary E, Genrich Michael P, Patek Emily, Bult Carol J
The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Genome Biol. 2009;10(8):R84. doi: 10.1186/gb-2009-10-8-r84. Epub 2009 Aug 14.
Linking biochemical genetic data to the reference genome for the laboratory mouse is important for comparative physiology and for developing mouse models of human biology and disease. We describe here a new database of curated metabolic pathways for the laboratory mouse called MouseCyc http://mousecyc.jax.org. MouseCyc has been integrated with genetic and genomic data for the laboratory mouse available from the Mouse Genome Informatics database and with pathway data from other organisms, including human.
将生化遗传数据与实验室小鼠的参考基因组相联系,对于比较生理学以及开发人类生物学和疾病的小鼠模型而言至关重要。我们在此描述了一个名为MouseCyc(http://mousecyc.jax.org)的关于实验室小鼠的精心策划的代谢途径新数据库。MouseCyc已与可从小鼠基因组信息数据库获取的实验室小鼠的遗传和基因组数据以及包括人类在内的其他生物的途径数据整合在一起。