Fluminense Federal University, Rio de Janeiro, RJ, Brazil.
Braz Oral Res. 2009 Apr-Jun;23(2):149-54. doi: 10.1590/s1806-83242009000200010.
The prevalence of HIV-related oral lesions may vary according to socioeconomic status and antiretroviral therapy, among other factors. This study's intent was to evaluate the association between socioeconomic indicators, CD4+ counts and HIV-related oral lesions in the city of Rio de Janeiro, RJ, Brazil. A retrospective epidemiological analysis was performed of the medical records of HIV-positive patients that attended the Federal University of Rio de Janeiro between 1997 and 2004. Gender, age, mode of HIV transmission, level of education, monthly familial income, CD4+ counts and HIV-related oral lesions were assessed. For statistical analysis, the Chi-square test was used with a level of significance of 5%. 254 medical records were reviewed: 83 women and 171 men. Monthly familial income below 2 minimum wages was associated with a higher prevalence of pseudomembranous candidiasis (p = 0.024), while income above 10 minimum wages was associated with a higher prevalence of salivary gland disease (p = 0.021). Lower socioeconomic status was associated with lower CD4+ counts (p = 0.017). In this study, an association was noted between socioeconomic status, immune suppression and prevalence of oral lesions. However, further studies are warranted using other socioeconomic variables in order to better assess this relationship.
HIV 相关口腔病变的流行率可能因社会经济地位和抗逆转录病毒治疗等因素而异。本研究旨在评估巴西里约热内卢市的社会经济指标、CD4+计数与 HIV 相关口腔病变之间的关联。对 1997 年至 2004 年间在里约热内卢联邦大学就诊的 HIV 阳性患者的病历进行了回顾性流行病学分析。评估了性别、年龄、HIV 传播途径、受教育程度、月家庭收入、CD4+计数和 HIV 相关口腔病变。统计分析采用卡方检验，显著性水平为 5%。共回顾了 254 份病历：83 名女性和 171 名男性。月家庭收入低于 2 最低工资与假膜性念珠菌病的更高患病率相关（p = 0.024），而收入高于 10 最低工资与唾液腺疾病的更高患病率相关（p = 0.021）。较低的社会经济地位与较低的 CD4+计数相关（p = 0.017）。在这项研究中，社会经济地位、免疫抑制和口腔病变的流行率之间存在关联。然而，需要进一步研究使用其他社会经济变量来更好地评估这种关系。
