Pardi Darrell S, D'Haens Geert, Shen Bo, Campbell Simon, Gionchetti Paolo
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA.
Inflamm Bowel Dis. 2009 Sep;15(9):1424-31. doi: 10.1002/ibd.21039.
When surgery is necessary in patients with ulcerative colitis, total proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the procedure of choice. Several inflammatory and noninflammatory complications can occur after IPAA. Pouchitis is the most common, occurring in approximately 50% of patients. Whereas "acute" pouchitis can be treated rapidly and successfully in the majority of patients, "refractory" and "chronic pouchitis" remain therapeutic challenges to patients and physicians. This article reviews the literature and offers consensus guidelines on issues related to the epidemiology, diagnosis, pathogenesis, risk factors, and treatment of pouchitis.
对于溃疡性结肠炎患者而言，当有必要进行手术时，全直肠结肠切除加回肠储袋肛管吻合术（IPAA）是首选术式。IPAA术后可能会出现多种炎症性和非炎症性并发症。储袋炎最为常见，约50%的患者会发生。虽然大多数患者的“急性”储袋炎能够迅速且成功地得到治疗，但“难治性”和“慢性储袋炎”对患者和医生来说仍是治疗难题。本文回顾了相关文献，并就储袋炎的流行病学、诊断、发病机制、危险因素及治疗等相关问题提供了共识性指南。
