Langdon James, Way Adam, Heaton Samuel, Bernard Jason, Molloy Sean
Specialist Registrar in Trauma and Orthopaedics, The Spinal Deformity Unit, The Royal National Orthopaedic Hospital, Brockley Hill, Stanmore HA7 4LP, UK.
Ann R Coll Surg Engl. 2009 Nov;91(8):649-52. doi: 10.1308/003588409X432482. Epub 2009 Aug 14.
Osseous metastases occur in 50% of patients with renal cell carcinoma; of these, 15% occur in the spine. The treatment options for spinal metastases secondary to renal cell carcinoma are limited. This paper considers the current management options available for spinal metastases secondary to renal cell carcinoma.
A review of four patients with spinal metastases secondary to renal cell carcinoma.
The presentation of four cases highlighting the current management options for spinal metastases secondary to renal cell carcinoma.
Historically, spinal metastases from renal cell carcinoma have been poorly managed; however, as the treatment of the primary disease improves, better treatment of the secondary disease is needed. Cement augmentation, used alone for prophylactic stabilisation or in conjunction with a posterior decompression and fixation, provides a useful addition in the management of these patients optimising their chance to remain ambulant, continent, and pain-free.
50%的肾细胞癌患者会发生骨转移;其中,15%发生在脊柱。肾细胞癌继发脊柱转移的治疗选择有限。本文探讨了肾细胞癌继发脊柱转移目前可用的治疗方案。
回顾4例肾细胞癌继发脊柱转移患者的情况。
4例病例的呈现突出了肾细胞癌继发脊柱转移目前的治疗方案。
从历史上看,肾细胞癌脊柱转移的治疗效果不佳;然而,随着原发性疾病治疗方法的改进,继发性疾病也需要更好的治疗。骨水泥强化单独用于预防性稳定或与后路减压及固定联合使用,在这些患者的治疗中是一种有益的补充,可优化他们保持行走、控便和无痛的机会。