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D型人格与外周动脉疾病患者的死亡率:一项初步研究。

Type D personality and mortality in peripheral arterial disease: a pilot study.

作者信息

Aquarius Annelies E, Smolderen Kim G, Hamming Jaap F, De Vries Jolanda, Vriens Patrick W, Denollet Johan

机构信息

Center of Research on Psychology in Somatic Diseases, Department of Medical Psychology, Tilburg University, PO Box 90153, 5000 LE Tilburg, the Netherlands.

出版信息

Arch Surg. 2009 Aug;144(8):728-33. doi: 10.1001/archsurg.2009.75.

Abstract

BACKGROUND

Type D personality refers to the tendency to experience negative emotions and to inhibit self-expression in social interaction and has been shown to be an independent predictor of mortality in cardiac disease. Information about the effects of psychological traits on prognosis is lacking in cases of peripheral arterial disease (PAD).

OBJECTIVE

To examine whether type D personality predicts all-cause mortality in PAD.

DESIGN

Pilot follow-up study.

SETTING

Vascular surgery department of a teaching hospital.

PATIENTS

A total of 184 patients with symptomatic PAD (mean [SD] age, 64.8 [9.8] years) were followed up for 4 years (interquartile range, 3.5-4.5 years).

MAIN OUTCOME MEASURES

Patients completed the type D Scale-14 measure of type D personality at baseline. Information about all-cause mortality was obtained from patient medical files.

RESULTS

During 4-year follow-up, 16 patients (8.7%) died. Adjusting for age and sex, type D personality was predictive of mortality (P = .03). Ankle-brachial index (P = .05), age (P = .009), diabetes mellitus (P = .02), pulmonary disease (P = .09), and renal disease (P = .02) were also predictive of mortality. Multivariable logistic regression revealed that age, diabetes, and renal disease were independent predictors of all-cause mortality (odds ratios, 1.1-2.3). After adjustment for these clinical predictors, patients with type D personality still had a more than 3-fold increased risk of death (odds ratio, 3.5; 95% confidence interval, 1.1-11.1; P = .04).

CONCLUSIONS

Type D personality predicts an increased risk of all-cause mortality in PAD, above and beyond traditional risk factors. Further research is needed to confirm these findings, but this pilot study suggests that the assessment of type D personality may be useful for detecting high-risk patients with PAD.

摘要

背景

D型人格是指在社交互动中体验负面情绪并抑制自我表达的倾向,已被证明是心脏病死亡率的独立预测因素。关于心理特质对周围动脉疾病(PAD)预后影响的信息尚缺乏。

目的

研究D型人格是否可预测PAD患者的全因死亡率。

设计

试点随访研究。

地点

一所教学医院的血管外科。

患者

共184例有症状的PAD患者(平均[标准差]年龄为64.8[9.8]岁)接受了4年随访(四分位间距为3.5 - 4.5年)。

主要观察指标

患者在基线时完成D型人格量表-14评估。从患者病历中获取全因死亡率信息。

结果

在4年随访期间,16例患者(8.7%)死亡。校正年龄和性别后,D型人格可预测死亡率(P = 0.03)。踝臂指数(P = 0.05)、年龄(P = 0.009)、糖尿病(P = 0.02)、肺部疾病(P = 0.09)和肾脏疾病(P = 0.02)也可预测死亡率。多变量逻辑回归显示,年龄、糖尿病和肾脏疾病是全因死亡率的独立预测因素(比值比为1.1 - 2.3)。校正这些临床预测因素后,D型人格患者的死亡风险仍增加3倍以上(比值比为3.5;95%置信区间为1.1 - 11.1;P = 0.04)。

结论

D型人格可预测PAD患者全因死亡率增加,超出传统危险因素。需要进一步研究来证实这些发现,但这项试点研究表明,评估D型人格可能有助于检测PAD高危患者。

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