David Doina, Clayman Lewis, Saleh Husain
Department of Pathology, Sinai-Grace Hospital/Detroit Medical Center, Wayne State University School of Medicine, Detroit, Michigan 48235, USA.
Diagn Cytopathol. 2010 Feb;38(2):81-4. doi: 10.1002/dc.21163.
Low-grade mucoepidermoid carcinoma (LG MEC) is a rare tumor which can occur in the minor salivary glands as intraoral lesion, more frequently in the palate and very rarely in the floor of the mouth. Traditionally, the diagnosis has been made on surgical resection specimens only. There is new growing evidence that these lesions can be accurately diagnosed by a fine-needle aspiration (FNA) biopsy procedure. In this article, we report a case of LG MEC of the floor of mouth diagnosed by FNA and confirmed by subsequent surgical resection. We also provide clues for high index of suspicion for these rare lesions, both clinically and morphologically.
低级别黏液表皮样癌（LG MEC）是一种罕见肿瘤，可作为口腔内病变发生于小唾液腺，更常见于腭部，极少发生于口底。传统上，仅通过手术切除标本进行诊断。越来越多的新证据表明，这些病变可通过细针穿刺抽吸（FNA）活检程序准确诊断。在本文中，我们报告了1例经FNA诊断并经后续手术切除证实的口底LG MEC病例。我们还从临床和形态学方面为这些罕见病变的高怀疑指数提供了线索。
