Halpern James, Salim Asad
Department of Dermatology, University Hospital of North Staffordshire, Stoke-on-Trent, United Kingdom.
Pediatr Dermatol. 2009 Jul-Aug;26(4):452-7. doi: 10.1111/j.1525-1470.2009.00952.x.
We report on an 18-month-old boy with a typical presentation of Sweet syndrome following an upper respiratory tract illness. No evidence of hematologic malignancy was found and he was successfully treated with oral prednisolone. A comprehensive literature review has summarized the features of pediatric Sweet syndrome from 66 reported cases. Cases occurring under the age of 3 years had a male predominance and no association with malignancy, whereas cases over the age of 3 years had an equal sex distribution and were strongly associated with myeloid line hematologic malignancies. Identified complications were serious with an overall mortality of 9% rising to 40% with cardiovascular involvement.
我们报告了一名18个月大的男孩，在上呼吸道疾病后出现了典型的Sweet综合征表现。未发现血液系统恶性肿瘤的证据，他接受口服泼尼松龙治疗后成功康复。一项全面的文献综述总结了66例报告的小儿Sweet综合征的特征。3岁以下的病例以男性为主，与恶性肿瘤无关，而3岁以上的病例性别分布均等，与髓系血液系统恶性肿瘤密切相关。已确定的并发症很严重，总体死亡率为9%，心血管受累时死亡率升至40%。
