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通过毒理学尿液分析确诊的两只狗的巴比妥酸盐中毒。

Barbiturate intoxication in two dogs confirmed by toxicological urinalysis.

作者信息

Brauer C, Tipold A, Desel H, Stein V M

机构信息

Department of Small Animal Medicine and Surgery, University of Veterinary Medicine Hannover, Bischofsholer Damm, Hannover, Germany.

出版信息

J Small Anim Pract. 2009 Aug;50(8):423-5. doi: 10.1111/j.1748-5827.2009.00749.x.

Abstract

Two dogs were presented within 24 hours to the Department of Small Animal Medicine and Surgery at the University of Veterinary Medicine Hannover for investigation of the sudden onset of neurological abnormalities following a walk in the same park. One dog was observed ingesting a piece of meat. Analysis of urine by gas chromatography-mass spectrometry from each of the dogs identified the presence of barbiturates. Both dogs recovered with supportive treatment. This is the first report to describe the use of toxicological urinalysis with gas chromatography-mass spectrometry for the diagnosis of barbiturate intoxication in dogs.

摘要

两只狗在24小时内被送到汉诺威兽医学院小动物医学与外科学系,它们在同一个公园散步后突然出现神经功能异常,需要进行检查。其中一只狗被观察到吞食了一块肉。通过气相色谱-质谱联用仪对每只狗的尿液进行分析,发现了巴比妥类药物的存在。两只狗经过支持性治疗后康复。这是第一份描述使用气相色谱-质谱联用仪进行毒理学尿液分析来诊断犬巴比妥类药物中毒的报告。

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