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执行功能与强迫症:论亚临床症状及其他伴随因素的重要性。

Executive functions and the obsessive-compulsive disorder: on the importance of subclinical symptoms and other concomitant factors.

作者信息

Bédard Marie-Josée, Joyal Christian C, Godbout Lucie, Chantal Sophie

机构信息

Department of Psychology, Université du Québec à Trois-Rivières, Quebec, Canada.

出版信息

Arch Clin Neuropsychol. 2009 Sep;24(6):585-98. doi: 10.1093/arclin/acp052. Epub 2009 Aug 18.

Abstract

Although reviews concerning the neuropsychology of obsessive-compulsive disorder (OCD) put great emphasis on impaired executive functioning, the overall conclusions are notoriously divergent. The main goal of the present study was to use a battery of neuropsychological tasks to assess nine cognitive domains with a special focus on executive functions in 40 patients with OCD. A secondary objective was to examine the relationships between clinical or demographic variables and neuropsychological performances. The third goal was to separate executive functions in more homogeneous components to verify whether specific impairment might be found in persons with OCD. Confirming the main hypothesis, few neuropsychological differences emerged between the OCD and healthy participants when concomitant factors were controlled. Moreover, subclinical symptoms appeared to play a different and independent role on the cognitive results. Future studies should include more specific tasks of lower-order executive functions among persons with OCD to confirm this possibility.

摘要

尽管有关强迫症(OCD)神经心理学的综述非常强调执行功能受损,但总体结论却存在显著分歧。本研究的主要目的是使用一系列神经心理学任务来评估40名强迫症患者的九个认知领域,特别关注执行功能。次要目标是检查临床或人口统计学变量与神经心理学表现之间的关系。第三个目标是将执行功能分离为更同质的成分,以验证强迫症患者是否存在特定损伤。证实了主要假设,在控制伴随因素后,强迫症患者与健康参与者之间几乎没有出现神经心理学差异。此外,亚临床症状似乎在认知结果中发挥了不同且独立的作用。未来的研究应在强迫症患者中纳入更多关于低阶执行功能的特定任务,以证实这种可能性。

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