Tsunoda Akira, Kamiyama Goichi, Narita Kazuhiro, Watanabe Makoto, Nakao Kentaro, Kusano Mitsuo
Department of Gastroenterological and General Surgery, Showa University School of Medicine, Tokyo, Japan.
Dis Colon Rectum. 2009 Sep;52(9):1572-7. doi: 10.1007/DCR.0b013e3181a909d4.
Functional outcome after low anterior resection with side-to-end anastomosis is comparable with that after a colonic J-pouch construction. The optimum size of the side limb has yet to be determined. This prospective randomized trial compared a 3-cm (short) and 6-cm (long) side limb.
Forty-four patients with a mid or low rectal cancer undergoing low anterior resection were randomly assigned to each group. Physiologic and clinical assessments were performed preoperatively and at 3, 6, and 12 months after ileostomy closure. Defecography was performed at six months after ileostomy closure.
Twenty patients in each group completed the study. Among them, one patient with a short limb and two others with a long limb developed leakage. Sphincter function and reservoir function were similar between the groups. Bowel function or incontinence scoring was similar between the groups. The incidence of incomplete evacuation assessed by defecography in the long limb group was significantly greater than in the short limb group (13/20 long and 5/20 short, P = 0.025). One patient in the long limb group experienced fecal impaction.
The study showed similar clinical results in patients with either a short limb or a long limb but seemed to be underpowered. A long limb may be associated with fecal impaction in patients undergoing low anterior resection with side-to-end anastomosis.
低位前切除端端吻合术后的功能结局与结肠J袋重建术后相当。侧支的最佳长度尚未确定。这项前瞻性随机试验比较了3厘米(短)和6厘米(长)的侧支。
44例中低位直肠癌患者接受低位前切除,随机分为两组。在术前以及回肠造口关闭后3个月、6个月和12个月进行生理和临床评估。在回肠造口关闭后6个月进行排粪造影。
每组20例患者完成研究。其中,1例短侧支患者和2例长侧支患者发生渗漏。两组之间的括约肌功能和储袋功能相似。两组之间的肠道功能或失禁评分相似。通过排粪造影评估,长侧支组不完全排空的发生率显著高于短侧支组(长侧支组13/20,短侧支组5/20,P = 0.025)。长侧支组有1例患者发生粪便嵌塞。
该研究表明,短侧支或长侧支患者的临床结果相似,但样本量似乎不足。对于接受低位前切除端端吻合术的患者,长侧支可能与粪便嵌塞有关。