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[抗青光眼药物中的防腐剂对眼表的影响]

[Effects of preservatives in anti-glaucoma agents on the ocular surface].

作者信息

Potop Vasile

机构信息

U.M.F Carol Davila Bucuresti.

出版信息

Oftalmologia. 2009;53(2):92-6.

PMID:19697847
Abstract

In POAG patients with long-term treatment may have an ocular surface damage, that undesirable effect may lead to treatment discontinuation and reduced quality of their life. Preservative free formulations in patients who are sensitive to preservatives because of pre-existing or concomitant ocular could be the gold standard. This article presents the results of a study which used Timabak as replacement therapy of BAK containing T/molol maleate in POAG patients. The effects of this replacement were studied in a subjective plan also with objective methods of tear film and ocular surface study

摘要

在长期接受治疗的开角型青光眼(POAG)患者中,可能会出现眼表损伤,这种不良影响可能导致治疗中断并降低其生活质量。对于因既往或伴随眼部疾病而对防腐剂敏感的患者,无防腐剂制剂可能是金标准。本文介绍了一项研究的结果,该研究使用替马巴(Timabak)作为POAG患者中含苯扎氯铵(BAK)的马来酸噻吗洛尔(T/molol maleate)的替代疗法。还通过泪膜和眼表研究的客观方法,在主观层面研究了这种替代的效果。

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