Moller James H, Shumway Sara J, Gott Vincent L
Department of Pediatrics, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Ann Thorac Surg. 2009 Sep;88(3):1044-6. doi: 10.1016/j.athoracsur.2009.05.077.
Between March 26, 1954 and July 19, 1955, C. Walton Lillehei and colleagues operated upon 45 infants and children with previously uncorrectable cardiac anomalies using cross-circulation with a human donor. Late follow-up was obtained in all of the 28 patients discharged after the operation. All of the 20 currently living patients were personally interviewed with regard to their cardiac status. Eight early survivors have died. Three died after repair of a residual cardiac anomaly. Another died 4 months postoperatively from heart failure. The other 4 died 13 to 47 years later: 2 of unknown causes, 1 of pneumonia, and 1 was an accident. Eleven late cardiac operations were performed. Seven were done to correct a residual anomaly. More than 40 years later, 2 patients underwent procedures to correct tricuspid regurgitation. One had a mitral valve procedure, and another underwent coronary artery bypass grafting. Of the current 20 survivors, none is limited from cardiac causes. Considering that these 45 patients represent "the dawn of open-heart surgery," the long-term results are quite remarkable.
1954年3月26日至1955年7月19日期间，C. 沃尔顿·利尔黑及其同事利用与人类供体的交叉循环技术，为45名患有此前无法矫正的心脏畸形的婴幼儿实施了手术。对术后出院的28名患者均进行了长期随访。对所有目前健在的20名患者就其心脏状况进行了个人访谈。8名早期幸存者已去世。3人死于残余心脏畸形修复术后。另1人术后4个月死于心力衰竭。其余4人在13至47年后死亡：2人死因不明，1人死于肺炎，1人死于意外事故。实施了11次晚期心脏手术。7次手术用于矫正残余畸形。40多年后，2名患者接受了矫正三尖瓣反流的手术。1人接受了二尖瓣手术，另1人接受了冠状动脉搭桥手术。在目前的20名幸存者中，无人因心脏问题而受限。鉴于这45名患者代表了“心脏直视手术的开端”，其长期结果相当显著。
