Freeman Daniel, Fowler David
Department of Psychology, Institute of Psychiatry, King's College London, London, UK.
Psychiatry Res. 2009 Sep 30;169(2):107-12. doi: 10.1016/j.psychres.2008.07.009. Epub 2009 Aug 22.
A social factor that has gained recent attention in understanding psychosis is trauma. In the current study the association of a history of trauma with persecutory ideation and verbal hallucinations was tested in the general public. Further, putative mediation variables including anxiety, depression and illicit drug use were examined. In a cross-sectional study, 200 members of the UK general public completed self-report questionnaires. A history of trauma was significantly associated with both persecutory ideation and hallucinations. Severe childhood sexual abuse and non-victimization events were particularly associated with psychotic-like experiences. The association of trauma and paranoia was explained by levels of anxiety. The association of trauma and hallucinations was not explained by the mediational variables. The study indicates that trauma may impact non-specifically on delusions via affect but that adverse events may work via a different route in the occurrence of hallucinatory experience. These ideas require tests in longitudinal designs.
在理解精神病方面，一个最近受到关注的社会因素是创伤。在当前研究中，在普通公众中测试了创伤史与被害妄想及言语幻觉之间的关联。此外，还检验了包括焦虑、抑郁和非法药物使用在内的假定中介变量。在一项横断面研究中，200名英国普通公众完成了自我报告问卷。创伤史与被害妄想和幻觉均显著相关。严重的童年性虐待和非受害事件尤其与类精神病体验相关。创伤与偏执狂之间的关联可由焦虑水平来解释。创伤与幻觉之间的关联无法由中介变量来解释。该研究表明，创伤可能通过情感非特异性地影响妄想，但不良事件在幻觉体验的发生中可能通过不同途径起作用。这些观点需要在纵向研究设计中进行检验。
