McAllen R M, Dampney R A
Howard Florey Institute of Physiology and Experimental Medicine, University of Melbourne, Vic., Australia.
Neurosci Lett. 1990 Mar 2;110(1-2):91-6. doi: 10.1016/0304-3940(90)90793-9.
Microinjections of sodium glutamate (200-800 pmol) were made into sites within the rostral ventrolateral medulla of anaesthetized cats in which the adrenal glands had been removed and the baroreceptors denervated, while arterial pressure, renal sympathetic nerve activity and hindlimb and forelimb blood flows were measured. Hindlimb and forelimb vascular resistances were affected in a parallel fashion by injections at different sites, but there was a clear dissociation between evoked changes in renal nerve activity and either forelimb or hindlimb vascular resistance. The results indicate that ventrolateral medullary vasomotor neurons are organized topographically with respect to the type, rather than body position, of the vascular beds they control.
将谷氨酸钠(200 - 800皮摩尔)微量注射到已摘除肾上腺且压力感受器去神经支配的麻醉猫延髓头端腹外侧的部位,同时测量动脉血压、肾交感神经活动以及后肢和前肢的血流。不同部位的注射以平行方式影响后肢和前肢血管阻力,但肾神经活动的诱发变化与前肢或后肢血管阻力之间存在明显分离。结果表明,延髓腹外侧血管运动神经元在其控制的血管床类型而非身体位置方面呈拓扑组织分布。