早期阿尔茨海默病和轻度认知障碍中的影像学与生物标志物
Imaging and biomarkers in early Alzheimer's disease and mild cognitive impairment.
作者信息
Petersen R C, Jack C R
机构信息
Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.
出版信息
Clin Pharmacol Ther. 2009 Oct;86(4):438-41. doi: 10.1038/clpt.2009.166. Epub 2009 Aug 26.
Abstract
A major focus of research on aging and dementia pertains to the prediction of future cognitive decline. Toward this end, several longitudinal studies are under way that are designed to explore early predictors of cognitive impairment. Neuroimaging techniques and biomarkers have shown promise in this application. Ultimately, it is likely that the use of a combination of neuroimaging and chemical biomarkers will be involved in predicting the development of dementia and Alzheimer's disease (AD).
摘要
衰老与痴呆研究的一个主要重点是预测未来的认知衰退。为此，正在进行几项纵向研究，旨在探索认知障碍的早期预测因素。神经成像技术和生物标志物在这一应用中已显示出前景。最终，使用神经成像和化学生物标志物的组合很可能会参与到痴呆症和阿尔茨海默病（AD）发展的预测中。
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