Hall W T, Mundon F K, Madden D L, DeSouza D, Kane J L
J Clin Microbiol. 1977 Aug;6(2):132-5. doi: 10.1128/jcm.6.2.132-135.1977.
Plasma samples from 245 regular plasma donors for Plasma Alliance, Inc. (Knoxville, Tenn.) were tested for the presence of antibody to hepatitis A antigen. Antibody was detected at an immune adherence hemagglutination titer of 1:10 or greater in 37% (91 of 245) of the donors. A statistically significant difference in the frequency of anti-hepatitis A was found between the 18- to 29-year-old group (30%) and the 30- to 49-year-old group (57%). No significant differences between whites and blacks or males afemales were observed. Eighty percent of the donors were in the age range of 18 to 29 years, whereas 48% of the higher-titered plasmas (1:1,000 or greater) were in the 30 to 49 age group. By preselection of donors, it would be possible to produce an immune serum globulin with a specific anti-hepatitis A titer.
对田纳西州诺克斯维尔市血浆联盟公司的245名常规血浆捐献者的血浆样本进行了甲型肝炎抗原抗体检测。在37%（245名中的91名）的捐献者中，以免疫粘连血凝滴度1:10或更高检测到抗体。在18至29岁组（30%）和30至49岁组（57%）之间，抗甲型肝炎的频率存在统计学上的显著差异。未观察到白人与黑人或男性与女性之间有显著差异。80%的捐献者年龄在18至29岁之间，而48%的高滴度血浆（1:1000或更高）来自30至49岁年龄组。通过预先筛选捐献者，有可能生产出具有特定抗甲型肝炎滴度的免疫血清球蛋白。
