百日咳博德特氏菌的淋巴细胞增多促进因子：分离、特性鉴定及生物学活性
Lymphocytosis-promoting factor of Bordetella pertussis: isolation, characterization, and biological activity.
作者信息
Morse S I
出版信息
J Infect Dis. 1977 Aug;136 Suppl:S234-8. doi: 10.1093/infdis/136.supplement.s234.
Abstract
The leukocytosis and lymphocytosis-promoting factor (LPF) of Bordetella pertussis has been isolated in apparently pure form. LPF is a protein essentially free of lipid and carbohydrate with an estimated molecular weight of 67,000-73,600 daltons. Purified LPF induced both histamine sensitization and refractoriness to epinephrine-induced hyperglycemia and was a murine thymus-derived (T-) cell mitogen. Adenyl cyclase activity also appeared to be associated with LPF.
摘要
百日咳博德特氏菌的白细胞增多和淋巴细胞增多促进因子（LPF）已以明显纯的形式分离出来。LPF是一种基本上不含脂质和碳水化合物的蛋白质，估计分子量为67,000 - 73,600道尔顿。纯化的LPF既诱导组胺致敏，又导致对肾上腺素诱导的高血糖症产生不应性，并且是一种源自鼠胸腺的（T）细胞有丝分裂原。腺苷酸环化酶活性似乎也与LPF有关。
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