Department of Chemistry, University of Rajasthan, Jaipur, India.
Ultrason Sonochem. 2010 Feb;17(2):399-402. doi: 10.1016/j.ultsonch.2009.08.003. Epub 2009 Aug 9.
An aqueous mediated novel synthesis of substituted 2'amino-4'benzoyl-2'-methyl spiro[indole 3,5'-[1,3]oxathiolane]-2(1H)-ones (2a-f) was carried out from the reaction of spiro [indole-3,2'-oxiranes] (1a-f) with thioacetamide in the presence of LiBr as catalyst. The reaction was carried out under both microwaves and sonication and results were also compared with conventional method. In general, improvement in rate and yields observed when reaction was carried out under sonication as compared to microwave irradiation and conventional method.
采用水相介导的方法，从螺[吲哚-3,2'-环氧乙烷]（1a-f）与硫代乙酰胺在 LiBr 作为催化剂的条件下反应，合成了取代的 2'-氨基-4'-苯甲酰基-2'-甲基螺[吲哚 3,5'-[1,3]氧硫杂环戊烷]-2(1H)-酮（2a-f）。该反应在微波和超声条件下都进行了研究，并与传统方法进行了比较。通常，与微波辐射和传统方法相比，超声条件下反应的速率和产率都有所提高。
