Department of Chemistry, KN Toosi University of Technology, Tehran, Iran.
Ultrason Sonochem. 2010 Feb;17(2):306-9. doi: 10.1016/j.ultsonch.2009.10.004. Epub 2009 Oct 13.
An efficient and green procedure has been developed for the synthesis of 1,8-dioxo-octahydroxanthenes derivatives. The reaction was carried out in water under ultrasound irradiation, using nanosized MCM-41-SO(3)H. In this method, several types of aromatic aldehyde, containing electron-withdrawing groups as well as electron-donating groups, were rapidly converted to the corresponding 1,8-dioxo-octahydroxanthenes in good to excellent yields. This novel synthetic method is especially favored because it provides a synergy of the nanosized MCM-41-SO(3)H and ultrasound irradiation which offers the advantages of high yields, short reaction times, simplicity and easy workup compared to the conventional methods reported in the literature.
已经开发出一种用于合成 1,8-二氧代-octahydroxanthenes 衍生物的高效、绿色的方法。该反应在超声辐射下于水中进行，使用纳米级 MCM-41-SO(3)H。在该方法中，几种类型的芳香醛，包括吸电子基团和供电子基团，迅速转化为相应的 1,8-二氧代-octahydroxanthenes，产率良好至优秀。这种新颖的合成方法特别受欢迎，因为它提供了纳米级 MCM-41-SO(3)H 和超声辐射的协同作用，与文献中报道的常规方法相比，具有高产率、短反应时间、简单和易于后处理的优点。
