Tsuno Yusuke, Mori Kensaku
Department of Physiology; Graduate School of Medicine; University of Tokyo; Tokyo, Japan.
Commun Integr Biol. 2009 Jul;2(4):362-4. doi: 10.4161/cib.2.4.8719.
Changes in behavioral state are accompanied by coordinated changes in the information processing mode in the hippocampus and neocortex of the brain. We review here the recent progress in the knowledge of behavioral state-dependent changes in the information processing mode in the central olfactory system. Olfactory cortex shows state-dependent gating of afferent sensory inputs. In the olfactory bulb, granule-to-mitral dendrodendritic synaptic inhibition is enhanced and the frequency of synchronized oscillatory activity of bulbar output neurons decreases during slow-wave sleep or deeply anesthetized state. These results suggest that the information processing mode in the whole olfactory system changes in a behavioral state-dependent manner to keep the neuronal circuits functioning optimally in each behavioral state.
行为状态的变化伴随着大脑海马体和新皮质中信息处理模式的协同变化。在此，我们综述了中枢嗅觉系统中信息处理模式随行为状态变化的相关知识的最新进展。嗅觉皮质表现出传入感觉输入的状态依赖性门控。在嗅球中，在慢波睡眠或深度麻醉状态下，颗粒细胞到二尖瓣细胞的树突 - 树突突触抑制增强，嗅球输出神经元同步振荡活动的频率降低。这些结果表明，整个嗅觉系统中的信息处理模式以行为状态依赖的方式变化，以使神经元回路在每种行为状态下都能最佳地发挥作用。
