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印度南部 A 组和 C 组轮状病毒抗 VP6 IgG 抗体。

Anti-VP6 IgG antibodies against group A and group C rotaviruses in South India.

机构信息

Department of Gastrointestinal Sciences, Christian Medical College, Vellore, India.

出版信息

Epidemiol Infect. 2010 Mar;138(3):442-7. doi: 10.1017/S0950268809990732. Epub 2009 Sep 2.

Abstract

In an epidemiological survey from South India, 936 serum samples were tested for IgG against recombinant baculovirus-expressed VP6 proteins from human group A and group C rotaviruses. The overall seroprevalence for group A was 100% and for group C was 25.32% (95% CI 22.64-28.21). The lowest seroprevalence for group C was in children aged <10 years (16.79%). An age-related rise in seroprevalence in group C, but not group A, suggests different patterns of exposure. Seroprevalence was similar in rural and urban subjects, unlike the higher prevalence in rural subjects in studies elsewhere.

摘要

在一项来自印度南部的流行病学调查中,检测了 936 份血清样本,以检测针对人 A 组和 C 组轮状病毒的重组杆状病毒表达的 VP6 蛋白的 IgG。A 组的总体血清阳性率为 100%,C 组为 25.32%(95%CI 22.64-28.21)。C 组血清阳性率最低的是年龄<10 岁的儿童(16.79%)。C 组而非 A 组的血清阳性率随年龄的增长而上升,表明暴露模式不同。农村和城市人群的血清阳性率相似,与其他地方农村人群阳性率较高的研究结果不同。

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