Department of Orthodontics and Pediatric Dentistry, School of Dentistry, University of São Paulo, Av. Lineu Prestes, 2227, 05508-000 São Paulo, SP, Brazil.
Arch Oral Biol. 2009 Nov;54(11):997-1001. doi: 10.1016/j.archoralbio.2009.08.003. Epub 2009 Sep 1.
To assess the effect of a fluoride varnish and gel on the erosive wear of primary and permanent teeth.
Sixty human primary (n=30) and permanent (n=30) enamel specimens were randomly assigned to one of the following groups: APF gel (1.23% F), NaF varnish (2.26% F), and control (no treatment). Fluoride gel was applied for 4 min and fluoride varnish for 24 h. Six daily demineralisation-remineralization cycles of 5 min of immersion in a cola drink (pH 2.3) and 30 min in artificial saliva were conducted during 7 days. All specimens were stored in artificial saliva between and after cycles. Surface Knoop microhardness (%SMHC) readings were performed at baseline, 48 h and 7 days. Data were tested using ANOVA and Tukey's tests (p<0.05).
For primary enamel, the mean %SMHC (+/-SD) after 48 h and 7 days was, respectively: gel (31.0+/-14.4 and 36.9+/-7.5), varnish (26.7+/-9.5 and 38.3+/-8.7), and control (35.8+/-8.6 and 45.0+/-8.6). For permanent enamel, such values were: gel (37.5+/-7.7 and 27.8+/-7.5), varnish (31.7+/-9.6 and 27.4+/-11.1) and control (48.6+/-6.4 and 43.1+/-6.4). In primary enamel, erosion inhibition by fluoride was not significant at 48 h (p=0.203) and 7 days (p=0.082). In permanent specimens, both products showed a significant effect (p<0.001).
Both fluoride varnish and gel were able to inhibit erosive enamel loss but mainly in the permanent experimental groups. Primary and permanent enamel substrates reacted differently to both demineralization by a cola drink and remineralization by fluoridated compounds.
评估氟化物漆和凝胶对乳牙和恒牙腐蚀性磨损的影响。
将 60 个人类乳牙(n=30)和恒牙(n=30)釉质标本随机分为以下组之一:APF 凝胶(1.23% F)、NaF 漆(2.26% F)和对照组(无处理)。氟化物凝胶应用 4 分钟,氟化物漆应用 24 小时。在 7 天内进行了 6 个每日脱矿-再矿化循环,每次 5 分钟浸泡在可乐饮料(pH 2.3)中,30 分钟浸泡在人工唾液中。所有标本在循环之间和之后都储存在人工唾液中。在基线、48 小时和 7 天时进行表面 Knoop 显微硬度(%SMHC)读数。使用方差分析和 Tukey 检验(p<0.05)对数据进行测试。
对于乳牙釉质,48 小时和 7 天后的平均%SMHC(+/-SD)分别为:凝胶(31.0+/-14.4 和 36.9+/-7.5)、漆(26.7+/-9.5 和 38.3+/-8.7)和对照组(35.8+/-8.6 和 45.0+/-8.6)。对于恒牙釉质,这些值分别为:凝胶(37.5+/-7.7 和 27.8+/-7.5)、漆(31.7+/-9.6 和 27.4+/-11.1)和对照组(48.6+/-6.4 和 43.1+/-6.4)。在乳牙釉质中,氟化物在 48 小时(p=0.203)和 7 天(p=0.082)时对腐蚀的抑制作用不显著。在恒牙标本中,两种产品均表现出显著效果(p<0.001)。
氟化物漆和凝胶均可抑制腐蚀性釉质丧失,但主要在永久性实验组中。可乐饮料引起的脱矿作用和氟化物化合物引起的再矿化作用对乳牙和恒牙基质的反应不同。