Magalhães A C, Stancari F H, Rios D, Buzalaf M A R
School of Dentistry of Araçatuba, UNESP - São Paulo State University, Araçatuba, SP, Brazil.
J Dent. 2007 Nov;35(11):858-61. doi: 10.1016/j.jdent.2007.08.005. Epub 2007 Sep 27.
This in vitro study assessed the effect of an experimental 4%TiF(4) varnish on enamel erosion.
Sixty bovine enamel blocks were randomly allocated to each type of varnish: Duraphat-D (NaF, 2.26%F), Duofluorid-F (NaF, 2.71% F), TiF(4)-T (2.45%F) and no-fluoride-P. After application of the varnishes, the blocks were subjected to six sequential pH cycles (cola drink for 10 min and artificial saliva for 50 min, each) per day, during 4 days. After the pH cycles, the blocks were maintained in artificial saliva for 18 h. Enamel alterations were determined in the 2nd and 4th days, using profilometry (wear) and microhardness (%SMHC) tests. Data were tested using ANOVA and Tukey's tests (p<0.05).
The mean %SMHC (+/-S.D.) at the 2nd and 4th day was, respectively, D (-77.26+/-5.04a and -88.59+/-5.11A), F (-76.79+/-7.82a and -88.78+/-6.10A), T (-88.28+/-3.19b and -92.04+/-2.54A,B) and P (-87.96+/-2.23b and -94.15+/-1.14B). The mean wear (microm+/-S.D.) at the 2nd and 4th day was, respectively, D (3.16+/-0.32a and 7.56+/-0.90A), F (3.35+/-0.78a,b and 7.92+/-0.98A), T (3.81+/-0.43b and 7.69+/-0.76A) and P (3.43+/-1.13a,b and 7.31+/-0.53A).
The NaF varnishes reduced the softening, but had no effect on the reduction of the wear. The TiF4 varnish was not able to reduce the softening and wear.
本体外研究评估了一种实验性4%四氟化钛（TiF₄）清漆对牙釉质侵蚀的影响。
将60个牛牙釉质块随机分配到每种清漆组：Duraphat - D（含2.26%氟的氟化钠）、Duofluorid - F（含2.71%氟的氟化钠）、TiF₄ - T（含2.45%氟）和无氟组 - P。涂抹清漆后，这些牙釉质块每天进行6个连续的pH循环（每次先在可乐饮料中浸泡10分钟，然后在人工唾液中浸泡50分钟），持续4天。pH循环结束后，将牙釉质块在人工唾液中保存18小时。在第2天和第4天，使用轮廓测定法（磨损）和显微硬度（%SMHC）测试来确定牙釉质的变化。数据采用方差分析和Tukey检验（p<0.05）。
第2天和第4天的平均%SMHC（±标准差）分别为：D组（-77.26±5.04a和-88.59±5.11A）、F组（-76.79±7.82a和-88.78±6.10A）、T组（-88.28±3.19b和-92.04±2.54A,B）和P组（-87.96±2.23b和-94.15±1.14B）。第2天和第4天的平均磨损（微米±标准差）分别为：D组（3.16±0.32a和7.56±0.90A）、F组（3.35±0.78a,b和7.92±0.98A）、T组（3.81±0.43b和7.69±0.76A）和P组（3.43±1.13a,b和7.31±0.53A）。
含氟化钠的清漆可减少牙釉质软化，但对减少磨损无作用。四氟化钛清漆无法减少牙釉质软化和磨损。
