Department of Operative Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Cap. Francisco Pedro S/N-Rodolfo Teófilo, Fortaleza, CE, 60430-170, Brazil.
Departament of Academic Master's Degree in Dental Sciences, Christus University Center-Unichristus, Fortaleza, CE, Brazil.
Eur Arch Paediatr Dent. 2021 Apr;22(2):157-162. doi: 10.1007/s40368-020-00536-8. Epub 2020 May 18.
Emerging data have suggested that acid erosion has become an increasing clinical problem in pediatric dentistry. This study aimed to investigate the abrasive effects of two commercial toothpastes on primary enamel eroded by orange juice using an in vitro model.
Thirty enamel slabs were obtained from primary teeth and then randomly assigned to three groups (n = 8) comprising two different toothpastes: G1-control-distilled water; G2-Dentifrice A (containing no fluoride); and G3-Dentifrice B (1.100 ppmF-NaF). Each slab had one half protected to provide a control side, and the other one was subjected to treatments. The slabs were submitted to daily erosive challenges (3×/day, 2 min) in concentrated orange juice (pH 3.38) associated with abrasive challenges using a tooth-brushing machine (150 brush movements for each cycle). During the experimental period, the slabs were kept in 37 °C artificial saliva, and the experiment was carried out for 5 days. The depths of the resulting eroded areas were measured by stylus profilometry. The data were analyzed using ANOVA and the Tukey-Kramer test (α = 5%).
Tooth loss (µm, mean ± SD) was 2.46 ± 1.18 for G1, 3.32 ± 2.12 for G2 and 2.14 ± 1.03 for G3. Therefore, the NaF dentifrice (Dentifrice B) produced significantly less mineral loss (p = 0.04) than dentifrice A.
The findings suggest that fluoride toothpaste could protect primary enamel against erosion.
新出现的数据表明，酸蚀已成为儿童牙科中日益严重的临床问题。本研究旨在通过体外模型研究两种市售牙膏对橙汁侵蚀的乳牙釉质的磨损作用。
从乳牙中获得 30 个釉质板，然后将其随机分为三组（n=8），包括两种不同的牙膏：G1-对照-蒸馏水；G2-牙膏 A（不含氟化物）；和 G3-牙膏 B（1.100 ppmF-NaF）。每个板的一半用保护剂保护作为对照侧，另一半进行处理。将板进行每日侵蚀挑战（每天 3 次，每次 2 分钟），在浓缩橙汁（pH 3.38）中进行，并使用牙刷机进行磨蚀挑战（每个周期进行 150 次刷牙运动）。在实验期间，将板保持在 37°C人工唾液中，实验进行了 5 天。使用触针轮廓仪测量产生的侵蚀区域的深度。使用方差分析和 Tukey-Kramer 检验（α=5%）对数据进行分析。
G1 的牙丢失量（µm，平均值±标准差）为 2.46±1.18，G2 为 3.32±2.12，G3 为 2.14±1.03。因此，含氟牙膏（牙膏 B）比牙膏 A 产生的矿物质损失明显更少（p=0.04）。
研究结果表明，氟化物牙膏可保护乳牙釉质免受侵蚀。
