Hofman Albert, Breteler Monique M B, van Duijn Cornelia M, Janssen Harry L A, Krestin Gabriel P, Kuipers Ernst J, Stricker Bruno H Ch, Tiemeier Henning, Uitterlinden André G, Vingerling Johannes R, Witteman Jacqueline C M
Department of Epidemiology, Erasmus Medical Center, PO Box 2040, 3000 CA Rotterdam. The Netherlands.
Eur J Epidemiol. 2009;24(9):553-72. doi: 10.1007/s10654-009-9386-z.
The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hepatic, neurological, ophthalmic, psychiatric and respiratory diseases. As of 2008, 14,926 subjects aged 45 years or over comprise the Rotterdam Study cohort. The findings of the Rotterdam Study have been presented in close to a 1,000 research articles and reports (see www.epib.nl/rotterdamstudy). This article gives the rationale of the study and its design. It also presents a summary of the major findings and an update of the objectives and methods.
鹿特丹研究是一项自1990年起在荷兰鹿特丹市开展的前瞻性队列研究。该研究的目标疾病包括心血管疾病、内分泌疾病、肝脏疾病、神经疾病、眼科疾病、精神疾病和呼吸系统疾病。截至2008年,鹿特丹研究队列由14,926名45岁及以上的受试者组成。鹿特丹研究的结果已发表在近1000篇研究文章和报告中(见www.epib.nl/rotterdamstudy)。本文阐述了该研究的基本原理及其设计。它还概述了主要研究结果,并更新了研究目标和方法。