Stein Cheryl R, Savitz David A, Janevic Teresa, Ananth Cande V, Kaufman Jay S, Herring Amy H, Engel Stephanie M
Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029-6574, USA.
Am J Obstet Gynecol. 2009 Dec;201(6):584.e1-9. doi: 10.1016/j.ajog.2009.06.047. Epub 2009 Sep 2.
We sought to examine the association between narrowly defined subsets of maternal ethnicity and birth outcomes.
We analyzed 1995-2003 New York City birth certificates linked to hospital discharge data for 949,210 singleton births to examine the multivariable associations between maternal ethnicity and preterm birth, subsets of spontaneous and medically indicated preterm birth, term small for gestational age, and term birthweight.
Compared with non-Hispanic whites, Puerto Ricans had an elevated odds ratio (1.9; 95% confidence interval, 1.9-2.0) for delivering at 32-36 weeks (adjusted for nativity, maternal age, parity, education, tobacco use, prepregnancy weight, and birth year). We found an excess of adverse outcomes among most Latino groups. Outcomes also varied within regions, with North African infants nearly 100 g (adjusted) heavier than sub-Saharan African infants.
The considerable heterogeneity in risk of adverse perinatal outcomes is obscured in broad categorizations of maternal race/ethnicity and may help to formulate etiologic hypotheses.
我们试图研究狭义定义的母亲种族亚组与出生结局之间的关联。
我们分析了1995 - 2003年纽约市的出生证明，并将其与949,210例单胎出生的医院出院数据相链接，以研究母亲种族与早产、自然早产和医学指征早产亚组、足月小样儿以及足月出生体重之间的多变量关联。
与非西班牙裔白人相比，波多黎各人在32 - 36周分娩的比值比升高（1.9；95%置信区间，1.9 - 2.0）（根据出生地、母亲年龄、产次、教育程度、吸烟情况、孕前体重和出生年份进行调整）。我们发现大多数拉丁裔群体中不良结局过多。不同地区的结局也有所不同，北非婴儿比撒哈拉以南非洲婴儿重近100克（调整后）。
围产期不良结局风险的显著异质性在母亲种族/民族的宽泛分类中被掩盖，这可能有助于形成病因假设。
