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消毒剂的杀病毒活性:针对脊髓灰质炎病毒的研究

Virucidal activity of disinfectants: studies with the poliovirus.

作者信息

Tyler R, Ayliffe G A, Bradley C

机构信息

Department of Medical Microbiology, Birmingham Medical School.

出版信息

J Hosp Infect. 1990 May;15(4):339-45. doi: 10.1016/0195-6701(90)90090-b.

DOI:10.1016/0195-6701(90)90090-b
PMID:1972949
Abstract

The activity of various disinfectants against poliovirus (Sabin 1 an) was assessed using surface and suspension tests. The surface test showed that 2% glutaraldehyde and high concentrations of hypochlorites (9200 ppm avCl2) were effective (i.e. greater than or equal to 4 log10 reduction) against a dried virus suspension in 1 min. Diluted aldehydes ('Sporicidin' and 'Gigasept'), lower hypochlorite concentrations (1000 ppm avCl2) and peroxides (3%) were less effective while 70% ethanol showed variable results; 70% isopropanol was ineffective in 10 min. In the suspension tests hydrogen peroxide (3% and 6%) and 70% ethanol were ineffective in 1 min.

摘要

使用表面和悬浮试验评估了各种消毒剂对脊髓灰质炎病毒(萨宾1型)的活性。表面试验表明,2%戊二醛和高浓度次氯酸盐(平均有效氯含量9200 ppm)在1分钟内对干燥病毒悬液有效(即减少量大于或等于4个对数10)。稀释的醛类消毒剂(“杀孢子剂”和“强力杀菌消毒剂”)、较低浓度的次氯酸盐(平均有效氯含量1000 ppm)和过氧化物(3%)效果较差,而70%乙醇的效果不一;70%异丙醇在10分钟内无效。在悬浮试验中,过氧化氢(3%和6%)和70%乙醇在1分钟内无效。

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