Fahoum Firas, Drory Vivian E, Issakov Josephine, Neufeld Miri Y
Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
J Clin Neuromuscul Dis. 2009 Sep;11(1):35-43. doi: 10.1097/CND.0b013e3181ae3be9.
Sarcoidosis is a multisystem inflammatory disease that can affect the nervous system. Cranial neuropathies are the most frequent presentation of neurosarcoidosis. Involvement of the peripheral nervous system is less common. The presentation is usually subacute or chronic sensorimotor axonal polyneuropathy, whereas acute polyradiculopathy is extremely rare. We report a case of Guillain-Barré-like syndrome probably secondary to sarcoidosis. A review of the literature revealed 9 similar cases. The possibility of a Guillain-Barré-like syndrome as a presenting symptom of sarcoidosis should be considered, especially in patients with atypical features such as cerebrospinal fluid pleocytosis.
结节病是一种可累及神经系统的多系统炎症性疾病。颅神经病变是神经结节病最常见的表现形式。外周神经系统受累则较少见。其表现通常为亚急性或慢性感觉运动轴索性多发性神经病，而急性多发性神经根病极为罕见。我们报告一例可能继发于结节病的格林-巴利综合征样病例。文献回顾显示有9例类似病例。应考虑格林-巴利综合征样综合征作为结节病首发症状的可能性，尤其是对于具有非典型特征（如脑脊液淋巴细胞增多）的患者。
