Pulmonary Department, Aristotle University of Thessaloniki, Thessaloniki, 57010 Greece.
Respirology. 2009 Nov;14(8):1208-11. doi: 10.1111/j.1440-1843.2009.01613.x. Epub 2009 Sep 1.
Ameloblastoma of the mandible is a rare odontogenic tumour that rarely metastasizes. We report a patient with a slowly progressing ameloblastoma of the mandible diagnosed at the age of seven and resected multiple times due to tumour recurrence. Multiple pulmonary metastatic nodules were resected at thoracotomy 27 years after the initial diagnosis; however, further pulmonary disease was discovered. The patient was admitted with chest pain due to pulmonary metastases 45 years after the initial diagnosis. The metastases were intraluminal and could be attributed to tumour cell aspiration during the surgical procedures on the mandible. The patient also suffered from hypercalcaemia which was attributed to a parathormone-like substance secreted by the tumour.
下颌骨造釉细胞瘤是一种罕见的牙源性肿瘤，很少发生转移。我们报告了一例下颌骨造釉细胞瘤患者，该患者在 7 岁时被诊断出患有进展缓慢的肿瘤，并因肿瘤复发而多次接受手术切除。在最初诊断后 27 年，因多发性肺转移结节而接受了开胸手术切除；然而，进一步发现肺部疾病。在最初诊断后 45 年，患者因肺转移引起胸痛而入院。转移灶位于管腔内，可归因于下颌骨手术过程中肿瘤细胞的吸入。患者还患有高钙血症，这归因于肿瘤分泌的甲状旁腺素样物质。
