Department of Stomatology, The Frist Affiliated Hosptial, Sun Yat-Sen University, Guangzhou, Guangdong 510080, People's Republic of China.
J Craniomaxillofac Surg. 2012 Dec;40(8):e470-4. doi: 10.1016/j.jcms.2012.03.006. Epub 2012 Apr 15.
Ameloblastomas have a high recurrence rate, and because of their biological tendency towards local invasion are considered borderline tumours. Despite this, reports of metastasis of these tumours are rare. This report presents a patient with mandibular ameloblastoma that recurred 29 years after surgery and metastasized to both lungs. Because of the large range of the area of metastasis, complete surgical resection of the tumours was impossible. After confirming the diagnosis by biopsy of the pulmonary lesions the pulmonary metastases were not treated actively. Observation over 4 years showed no obvious change in the lung metastasis. Recent cases are summarized and analyzed in this paper, with respect to its occurrence, pathological types, methods of treatment and other related aspects.
成釉细胞瘤有较高的复发率,且由于其具有局部侵袭的生物学倾向,被认为是交界性肿瘤。尽管如此,这些肿瘤转移的报告仍然很少见。本报告介绍了一例下颌骨成釉细胞瘤患者,该患者在手术后 29 年复发,并转移至双肺。由于转移范围广泛,无法进行肿瘤的完全手术切除。在对肺部病变进行活检以确认诊断后,并未积极治疗肺部转移。经过 4 年的观察,肺部转移没有明显变化。本文对近年来的病例进行了总结和分析,涉及发病情况、病理类型、治疗方法等相关方面。