Lopatkin N A, Borisenko N I, Gorodetskaia S B, Kondrat'eva E M
Urol Nefrol (Mosk). 1990 Mar-Apr(2):17-20.
The leading role of allergic components was established in some rare patterns of prostatitis. To develop the methods applicable for differential diagnosis of allergic prostatitis, the authors followed up 60 patients aged from 15 to 53 years who suffered from chronic prostatitis and 10 normal controls. The patients with bacterial disease, abacterial prostatitis with concurrent allergic components or subjects with allergic prostatitis were enrolled in the study. Immunoassay was an essential part in the diagnosis of allergic prostatitis. The study revealed a dramatic inhibition of ejaculate gamma-glutamine transferase in those who suffered from an abacterial pattern with allergic component and almost three-fold in those with allergic prostatitis. Certain though insignificant decrease in the ejaculate gamma-glutamine transferase was documented in patients with bacterial prostatitis. Investigations of ejaculate IgE revealed quite an opposite picture: 10-fold increase in IgE levels in the ejaculate of patients with allergic prostatitis as compared with other groups, controls in their number. Besides, patients with allergic prostatitis had three-fold higher IgE in the ejaculate than in the blood serum. The aforementioned phenomenon failed to be observed in patients with other patterns of prostatitis. Decreased ejaculate gamma-glutamine transferase and increased IgE can be regarded as criteria for differential diagnosis of allergic prostatitis.
在某些罕见类型的前列腺炎中，已证实过敏成分起主要作用。为了开发适用于过敏性前列腺炎鉴别诊断的方法，作者对60例年龄在15至53岁之间的慢性前列腺炎患者和10名正常对照进行了随访。患有细菌性疾病、伴有过敏成分的非细菌性前列腺炎的患者或患有过敏性前列腺炎的受试者被纳入研究。免疫测定是过敏性前列腺炎诊断的重要组成部分。研究发现，在患有伴有过敏成分的非细菌性前列腺炎的患者中，射精液γ-谷氨酰胺转移酶显著受到抑制，而在患有过敏性前列腺炎的患者中几乎增加了两倍。在细菌性前列腺炎患者中，射精液γ-谷氨酰胺转移酶有一定程度但不显著的下降。对射精液IgE的研究显示出完全相反的情况：与其他组（数量为对照组）相比，过敏性前列腺炎患者射精液中的IgE水平增加了10倍。此外，过敏性前列腺炎患者射精液中的IgE比血清中的高两倍。在其他类型前列腺炎患者中未观察到上述现象。射精液γ-谷氨酰胺转移酶降低和IgE升高可被视为过敏性前列腺炎鉴别诊断的标准。
