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[男性生殖系统慢性炎症性疾病鉴别诊断中器官特异性射精蛋白浓度的免疫化学测定]

[The immunochemical determination of the concentration of organ-specific ejaculate proteins in the differential diagnosis of chronic inflammatory diseases of the male reproductive system].

作者信息

Gal'kovich K R, Sosnin D Iu

出版信息

Urol Nefrol (Mosk). 1997 Sep-Oct(5):40-2.

PMID:9412014
Abstract

Concentrations of lactoferrin (LF), alpha-microglobulin of fertility (AMGF) and specific thermostable alpha-glycoprotein (STAG) which are markers of the prostate, seminal vesicles and testiculi in ejaculate, respectively, were determined by Ouchterlony's immunodiffusion method in 148 patients with chronic prostatitis (group 1), 26 patients with combination of prostatitis with chronic epididymitis (group 2) and 22 healthy controls (group 3). After that the patients were given prostatilen. It was found that high pretreatment values of LF registered in groups 1 and 2 lowered close to those in the controls. This shows elevated LF to be a diagnostic sign of prostatitis. In group 1 AMGF was lower than in controls, in groups 1, 2 and 3 STAG levels were similar.

摘要

采用双向免疫扩散法,对148例慢性前列腺炎患者(第1组)、26例前列腺炎合并慢性附睾炎患者(第2组)和22例健康对照者(第3组)的精液中乳铁蛋白(LF)、生育α-微球蛋白(AMGF)和特异性热稳定α-糖蛋白(STAG)的浓度进行了测定,这三种物质分别是前列腺、精囊和睾丸的标志物。之后,给予患者前列腺素。结果发现,第1组和第2组LF的预处理值较高,治疗后接近对照组水平。这表明LF升高是前列腺炎的诊断标志。第1组的AMGF低于对照组,第1组、第2组和第3组的STAG水平相似。

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