Snelling William J, Xiao Lihua, Ortega-Pierres Guadalupe, Lowery Colm J, Moore John E, Rao Juluri R, Smyth Stephen, Millar B Cherie, Rooney Paul J, Matsuda Motoo, Kenny Fiona, Xu Jiru, Dooley James S G
Centre for Molecular Biosciences, School of Biomedical Sciences, University of Ulster, Coleraine, Co. Londonderry, Northern Ireland.
J Infect Dev Ctries. 2007 Dec 1;1(3):242-56.
Globally, Cryptosporidium infection continues to be a significant health problem where it is recognized as an important cause of diarrhoea in both immunocompromised and immunocompetent people. In developing countries persistent diarrhoea is the leading cause of death in children younger than five years of age, where it accounts for 30 to 50 percent of those deaths. Encouragingly an increasing number of investigations in developing countries employ molecular tools, significantly improving the quality of epidemiological information. This improved Cryptosporidium monitoring, with appropriate molecular methods, in surface water, livestock, wildlife and humans, will increase current knowledge of infection and transmission patterns, and ultimately help to control Cryptosporidium via improved risk assessments in the future.
在全球范围内，隐孢子虫感染仍是一个重大的健康问题，在免疫功能低下和免疫功能正常的人群中，它被认为是腹泻的重要病因。在发展中国家，持续性腹泻是五岁以下儿童死亡的主要原因，占这些死亡人数的30%至50%。令人鼓舞的是，发展中国家越来越多的调查采用分子工具，显著提高了流行病学信息的质量。通过适当的分子方法，对地表水、家畜、野生动物和人类进行这种改进的隐孢子虫监测，将增加目前对感染和传播模式的了解，并最终通过未来改进的风险评估，有助于控制隐孢子虫。
