Kwag Jeehyun, Paulsen Ole
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Nat Neurosci. 2009 Oct;12(10):1219-21. doi: 10.1038/nn.2388. Epub 2009 Sep 6.
The method by which local networks in the brain store information from extrinsic afferent inputs is not well understood. We found that the timing of afferent input can bidirectionally control the sign of spike timing-dependent plasticity at local synapses in rat hippocampus. This mechanism provides a means by which temporal information in external input can be encoded in the local matrix of synaptic weights.
大脑中的局部网络存储来自外部传入输入信息的方式尚未得到充分理解。我们发现传入输入的时间可以双向控制大鼠海马体局部突触处依赖于尖峰时间的可塑性的符号。这种机制提供了一种手段，通过它外部输入中的时间信息可以被编码在突触权重的局部矩阵中。
