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IKKε：肥胖与炎症之间的桥梁。

IKKepsilon: a bridge between obesity and inflammation.

作者信息

Olefsky Jerrold M

机构信息

Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.

出版信息

Cell. 2009 Sep 4;138(5):834-6. doi: 10.1016/j.cell.2009.08.018.

DOI:10.1016/j.cell.2009.08.018
PMID:19737512
Abstract

Obesity leads to tissue inflammation and insulin resistance, which are features of metabolic diseases such as type 2 diabetes. Chiang et al. (2009) now show that the IkappaB kinase IKKepsilon is an important link between obesity and inflammation and may be a new therapeutic target for treating obesity-related metabolic diseases.

摘要

肥胖会导致组织炎症和胰岛素抵抗，而这正是诸如2型糖尿病等代谢性疾病的特征。蒋等人（2009年）现在表明，IκB激酶IKKε是肥胖与炎症之间的重要联系，并且可能是治疗肥胖相关代谢性疾病的一个新的治疗靶点。

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IKKepsilon: a bridge between obesity and inflammation.IKKε：肥胖与炎症之间的桥梁。
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