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患者接受经验性米卡芬净治疗时发生致命荚膜组织胞浆菌感染病例报告。

Case of fatal Blastoschizomyces capitatus infection occurring in a patient receiving empiric micafungin therapy.

机构信息

Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

出版信息

Antimicrob Agents Chemother. 2009 Dec;53(12):5306-7. doi: 10.1128/AAC.00710-09. Epub 2009 Sep 8.

Abstract

We report the first case, to our knowledge, of Blastoschizomyces capitatus infection occurring in a patient receiving empirical echinocandin therapy for neutropenic fevers. Clinicians should consider B. capitatus infection in those neutropenic patients who remain febrile despite echinocandin therapy or who develop yeast bloodstream infections while receiving an echinocandin.

摘要

我们报告了首例裂殖酵母感染病例,据我们所知,该病例发生在接受经验性棘白菌素治疗中性粒细胞减少性发热的患者中。对于那些尽管接受了棘白菌素治疗仍持续发热或在接受棘白菌素治疗时发生酵母血流感染的中性粒细胞减少患者,临床医生应考虑裂殖酵母感染。

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Effect of antifungal treatment in a murine model of blastoschizomycosis.抗真菌治疗在芽生裂殖菌病小鼠模型中的作用
Int J Antimicrob Agents. 2007 Jan;29(1):79-83. doi: 10.1016/j.ijantimicag.2006.08.025. Epub 2006 Nov 28.
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Invasive infections caused by Blastoschizomyces capitatus and Scedosporium spp.头裂殖酵母和帚霉属引起的侵袭性感染
Clin Microbiol Infect. 2004 Mar;10 Suppl 1:76-85. doi: 10.1111/j.1470-9465.2004.00842.x.
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Blastoschizomyces capitatus infection in acute leukemia patients.
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