Ghenghesh Khalifa Sifaw, Ahmed Salwa F, El-Khalek Rania Abdel, Al-Gendy Atef, Klena John
Dept. of Microbiology and Immunology, Faculty of Medicine, Al-Fateh University, Tripoli, Libya.
J Infect Dev Ctries. 2008 Apr 1;2(2):81-98.
Although their role in gastroenteritis is controversial, Aeromonas species are recognized as etiological agents of a wide spectrum of diseases in man and animals. In developing countries, potentially pathogenic Aeromonas sp. are very common in drinking water and in different types of foods, particularly seafood. Several food-borne and water-borne outbreaks as well nosocomial outbreaks associated with aeromonads have been reported. Significant association of Aeromonas sp. with diarrhoea in children has been reported from several countries. These organisms are important causes of skin and soft-tissue infections and aspiration pneumonia following contact with water and after floods. High incidence of antimicrobial resistance, including to third-generation cephalosporins and the fluoroquinolones, is found among Aeromonas sp. isolated from clinical sources in some developing countries in Asia. Isolating and identifying Aeromonas sp. to genus level is simple and requires resources that are available in most microbiology laboratories for processing common enteric bacteria. The present review will cover the epidemiology, clinical syndromes, low-cost diagnostic methods, and antimicrobial resistance and treatment of Aeromonas infections in developing countries.
虽然气单胞菌属在肠胃炎中的作用存在争议，但它们被公认为人和动物多种疾病的病原体。在发展中国家，潜在致病性气单胞菌在饮用水和不同类型的食物中非常常见，尤其是海鲜。已经报道了几起与气单胞菌相关的食源性和水源性暴发以及医院感染暴发。几个国家报告了气单胞菌属与儿童腹泻之间的显著关联。这些微生物是接触水后以及洪水后皮肤和软组织感染及吸入性肺炎的重要病因。在亚洲一些发展中国家，从临床来源分离出的气单胞菌属中发现了包括对第三代头孢菌素和氟喹诺酮类药物在内的高耐药率。将气单胞菌属分离并鉴定到属水平很简单，并且大多数微生物实验室都具备处理常见肠道细菌所需的资源。本综述将涵盖发展中国家气单胞菌感染的流行病学、临床综合征、低成本诊断方法以及抗菌药物耐药性和治疗。
