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[瑞得对类风湿关节炎患者心功能的影响(基于超声心动图数据)]

[The effect of Ridaura on cardiac function in patients with rheumatoid arthritis (based on echocardiographic data)].

作者信息

Nemchinov E N, Chichasova N V, Kanevskaia M Z, Slobodina G A

出版信息

Revmatologiia (Mosk). 1990 Jan-Mar(1):12-7.

PMID:1974083
Abstract

The method of echocardiography was used to study the effect of ridaura on the functional state of the heart in patients with rheumatoid arthritis (RA) depending on the duration of therapy and its efficacy. A total of 28 patients with RA were examined in the dynamics of therapy. The favourable effect of ridaura on the size of the left ventricle of the heart and its contractile function with the general positive effect of therapy was revealed. A decrease in the size of the left ventricle began 6 months after treatment with ridaura and continued up to the end of the first year, the contractile function considerably rose after two years of treatment. In 1/3 of the patients side effects developed; they manifested themselves in deterioration of the indices of hemodynamics. The unfavourable effect of ridaurotherapy on the myocardium had a latent course and was reversible.

摘要

采用超声心动图方法,根据治疗持续时间及其疗效,研究瑞得对类风湿关节炎(RA)患者心脏功能状态的影响。共对28例RA患者进行了治疗动态观察。结果显示,瑞得对心脏左心室大小及其收缩功能具有良好作用,且治疗总体呈阳性效果。使用瑞得治疗6个月后左心室大小开始减小,并持续至第一年末,治疗两年后收缩功能显著增强。1/3的患者出现了副作用,表现为血液动力学指标恶化。瑞得治疗对心肌的不良作用呈隐匿性病程且可逆。

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