Department of Cardiovascular Surgery, Nihon University School of Medicine, Tokyo 173-8610, Japan.
J Thorac Cardiovasc Surg. 2010 Jun;139(6):1494-500. doi: 10.1016/j.jtcvs.2009.07.039. Epub 2009 Sep 10.
ATS Medical, Inc, developed a mechanical heart valve that has been in use since 1992. In this article, we present the results of 15 years of follow-up of patients who have undergone ATS heart valve replacement at our hospital.
We performed ATS heart valve replacements on 231 patients between September 1993 and March 2008. Our operative mortality rate for the study period was 2.2%. The survival for postoperative thromboembolic events was 0.29%/pt-y for aortic valve replacement, 0.48%/pt-y for mitral, 0.80%/pt-y for double valve replacement, and overall 0.44%/pt-y. The survival after bleeding events was 0.29%/pt-y for aortic valve replacement, 0.16%/pt-y for mitral, 0%/pt-y for double valve replacement, and overall 0.19%/pt-y. Patient-prosthesis mismatch, as determined by echocardiography, was found in 83.3% of patients at 19 mm, but other sizes showed good valve function. Prosthetic valve noise was undetectable in 92.8% of patients, and quality of life was excellent.
Few prosthetic valve-related complications were seen with ATS heart valve replacements in this study, and the follow-up results were favorable. The international normalized ratio was maintained in the range 1.6 to 2.0 in patients with aortic valve replacement in sinus rhythm. Not only bleeding events, seen at a rate of 0.19%/pt-y, but also thromboembolic events, at 0.44%/pt-y, were low when compared with conventional mechanical valves. Prosthetic valve noise is low, and this appears to be an excellent mechanical valve from the quality of life standpoint. The ATS valve has an excellent safety profile when compared with other mechanical valves.
ATS 医疗公司开发了一种机械心脏瓣膜，自 1992 年以来一直在使用。在本文中，我们介绍了在我们医院接受 ATS 心脏瓣膜置换术的患者 15 年随访的结果。
我们在 1993 年 9 月至 2008 年 3 月期间对 231 例患者进行了 ATS 心脏瓣膜置换术。研究期间我们的手术死亡率为 2.2%。术后血栓栓塞事件的生存率为主动脉瓣置换术为 0.29%/pt-y，二尖瓣置换术为 0.48%/pt-y，双瓣置换术为 0.80%/pt-y，总生存率为 0.44%/pt-y。出血事件后的生存率为主动脉瓣置换术为 0.29%/pt-y，二尖瓣置换术为 0.16%/pt-y，双瓣置换术为 0%/pt-y，总生存率为 0.19%/pt-y。超声心动图显示，83.3%的患者存在 19mm 的患者-假体不匹配，但其他尺寸显示出良好的瓣膜功能。92.8%的患者听不到人工瓣膜噪音，生活质量极好。
在这项研究中，ATS 心脏瓣膜置换术的患者出现的人工瓣膜相关并发症较少，随访结果良好。在窦性心律的主动脉瓣置换术中，国际标准化比值维持在 1.6 至 2.0 之间。与传统的机械瓣膜相比，不仅出血事件的发生率为 0.19%/pt-y，血栓栓塞事件的发生率为 0.44%/pt-y 也较低。人工瓣膜噪音低，从生活质量的角度来看，这似乎是一种极好的机械瓣膜。与其他机械瓣膜相比，ATS 瓣膜具有极佳的安全性。
