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基于数据挖掘的药物不良事件检测。

Data-mining-based detection of adverse drug events.

作者信息

Chazard Emmanuel, Preda Cristian, Merlin Béatrice, Ficheur Grégoire, Beuscart Régis

机构信息

Medical Information and Records Department EA2694, University Hospital, 59000 Lille, France.

出版信息

Stud Health Technol Inform. 2009;150:552-6.

PMID:19745372
Abstract

Every year adverse drug events (ADEs) are known to be responsible for 98,000 deaths in the USA. Classical methods rely on report statements, expert knowledge, and staff operated record review. One of our objectives, in the PSIP project framework, is to use data mining (e.g., decision trees) to electronically identify situations leading to risk of ADEs. 10,500 hospitalization records from Denmark and France were used. 500 rules were automatically obtained, which are currently being validated by experts. A decision support system to prevent ADEs is then to be developed. The article examines a decision tree and the rules in the field of vitamin K antagonists.

摘要

众所周知,在美国,每年药物不良事件(ADEs)导致98,000人死亡。传统方法依赖于报告声明、专家知识以及工作人员进行的记录审查。在PSIP项目框架中,我们的目标之一是使用数据挖掘(例如决策树)来电子识别导致药物不良事件风险的情况。我们使用了来自丹麦和法国的10,500份住院记录。自动获取了500条规则,目前正由专家进行验证。随后将开发一个预防药物不良事件的决策支持系统。本文研究了维生素K拮抗剂领域的决策树和规则。

相似文献

1
Data-mining-based detection of adverse drug events.基于数据挖掘的药物不良事件检测。
Stud Health Technol Inform. 2009;150:552-6.
2
Detection of adverse drug events detection: data aggregation and data mining.药物不良事件检测:数据汇总与数据挖掘。
Stud Health Technol Inform. 2009;148:75-84.
3
Human factors methods to support the experts' review of automatically detected adverse drug events.支持专家对自动检测到的药物不良事件进行审查的人为因素方法。
Stud Health Technol Inform. 2009;150:542-6.
4
PSIP: an overview of the results and clinical implications.PSIP:结果与临床意义概述
Stud Health Technol Inform. 2011;166:3-12.
5
Data mining to generate adverse drug events detection rules.数据挖掘以生成药物不良事件检测规则。
IEEE Trans Inf Technol Biomed. 2011 Nov;15(6):823-30. doi: 10.1109/TITB.2011.2165727. Epub 2011 Aug 22.
6
Adverse drug events prevention rules: multi-site evaluation of rules from various sources.药物不良事件预防规则:对来自不同来源的规则进行多中心评估。
Stud Health Technol Inform. 2009;148:102-11.
7
The expert explorer: a tool for hospital data visualization and adverse drug event rules validation.专家探索器:一种用于医院数据可视化和药物不良事件规则验证的工具。
Stud Health Technol Inform. 2009;148:85-94.
8
Toward automatic detection and prevention of adverse drug events.迈向药物不良事件的自动检测与预防。
Stud Health Technol Inform. 2009;143:30-5.
9
A knowledge engineering framework towards clinical support for adverse drug event prevention: the PSIP approach.一种用于预防药物不良事件临床支持的知识工程框架:PSIP 方法。
Stud Health Technol Inform. 2009;148:131-41.
10
Detection of adverse drug events: proposal of a data model.药物不良事件的检测:一种数据模型的提议
Stud Health Technol Inform. 2009;148:63-74.

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Constructing Clinical Decision Support Systems for Adverse Drug Event Prevention: A Knowledge-based Approach.构建用于预防药物不良事件的临床决策支持系统:一种基于知识的方法。
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